Data Catalog

• Expression profiling of murine lung 70 days following exposure to fractionated or acute dose of 1.0 Gy 56Fe- particle irradiation

  NASA Test —

  Irradiation of the K-rasLA1 mouse model with a fractionated dose of 1.0Gy 56Fe- particles increases the incidence of invasive carcinoma compared to unirradiated...

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• Immune responses to the in vitro LPS assault engineered in the spaceflight multi-omics study

  NASA Test —

  Microgravity alters the immune response to in vitro LPS assault engineered in spaceflight: A multi-omics study Microgravity can facilitate creation of a potent...

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• Gene expression profiling of human peripheral blood lymphocytes cultured in modeled microgravity

  NASA Test —

  In the present study we analyzed miRNA and mRNA expression profiles in human peripheral blood lymphocytes (PBLs) incubated in microgravity condition simulated by a...

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• microRNA expression profiles in human peripheral blood lymphocytes cultured in modeled microgravity

  NASA Test —

  In the present study we analyzed miRNA and mRNA expression profiles in human peripheral blood lymphocytes (PBLs) incubated in microgravity condition simulated by a...

  • HTML

• Exposure to ionizing radiation induced persistent gene expression changes in mouse mammary gland

  NASA Test —

  Six to eight week old female C57BL/6J mice were exposed to 2 Gy of whole body xce xb3 radiation and mammary glands were surgically removed 2-month after radiation. RNA...

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• Gamma radiation and HZE treatment of seedlings in Arabidopsis

  NASA Test —

  Plants exhibit a robust transcriptional response to gamma radiation which includes the induction of transcripts required for homologous recombination and the...

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• Immediate Transcriptional Changes in Response to High Dose Radiation Exposure

  NASA Test —

  One of the most likely risks astronauts on long duration space missions face is exposure to ionizing radiation associated with highly energetic and charged heavy (HZE)...

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• Transcription profiling of human MCF10A cells subjected to ionizing radiation and treatment with transforming growth factor beta-1

  NASA Test —

  Transforming growth factor beta-1 (TGFbeta) is a tumor suppressor during the initial stage of tumorigenesis but it can switch to a tumor promoter during neoplastic...

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• Transcription profiling of human MCF10A cells subjected to ionizing radiation and treatment with transforming growth factor beta-1

  NASA Test —

  Transforming growth factor beta-1 (TGFbeta) is a tumor suppressor during the initial stage of tumorigenesis but it can switch to a tumor promoter during neoplastic...

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• Response to Low Shear Modeled Microgravity Indicates Translation of Lactobacillus acidophilus ATCC 4356 Benefits to Spaceflight

  NASA Test —

  The introduction of generally recognized as safe (GRAS) probiotic microbes into the spaceflight food system has the potential for use as a safe non-invasive daily...

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• Worms spun in centrifuge at elevated g values

  NASA Test —

  Worms spun at higher than normal g values for 4 days on 20G centrifuge vs. worms kept at 1 X G. Both are mixed stage cultures. A stimulus or stress experiment design...

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• Immediate Transcriptional Changes in Response to High Dose Radiation Exposure

  NASA Test —

  One of the most likely risks astronauts on long duration space missions face is exposure to ionizing radiation associated with highly energetic and charged heavy (HZE)...

  • HTML

• Environmental and simulation facility conditions can modulate a behavioral-driven altered gravity response of Drosophila imagoes transcriptome

  NASA Test —

  Genome-wide transcriptional profiling shows that reducing gravity levels in the International Space Station (ISS) causes important alterations in Drosophila gene...

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• Expression profiling of murine lung 70 days following exposure to fractionated or acute dose of 1.0 Gy 56Fe- particle irradiation

  NASA Test —

  Irradiation of the K-rasLA1 mouse model with a fractionated dose of 1.0Gy 56Fe- particles increases the incidence of invasive carcinoma compared to unirradiated...

  • HTML

• Effect of electromagnetic fields on the chondrogenic differentiation under microgravity conditions

  NASA Test —

  A combination therapy of electromagnetic fields (EMF) and simulated microgravity (SMG) has not been examined in regenerative medicine of cartilage. In the present...

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• Murine microenvironment metaprofiles associate with human cancer etiology and intrinsic subtypes

  NASA Test —

  We developed a mouse model that captures radiation effects on host biology by transplanting unirradiated Trp53 null mammary tissue to sham or irradiated hosts. Gene...

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• Immune responses to the in vitro LPS assault engineered in the spaceflight multi-omics study

  NASA Test —

  Microgravity alters the immune response to in vitro LPS assault engineered in spaceflight: A multi-omics study Microgravity can facilitate creation of a potent...

  • HTML

• Gravitational signature of synchronized cell cultures in particular cell cycle stages

  NASA Test —

  Cell cycle and cell proliferation are decoupled under altered gravity conditions. We have previously shown that semisolid cell cultures of Arabidopsis suffer overall...

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• Proton Irradiation Impacts Age Driven Modulations of Cancer Progression Influenced by Immune System Transcriptome Modifications from Splenic Tissue

  NASA Test —

  Age plays a crucial role in the interplay between tumor and host; with further perturbations induced by irradiation. Proton irradiation on tumors induces biological...

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• Gene expression profiling of human peripheral blood lymphocytes cultured in modeled microgravity

  NASA Test —

  In the present study we analyzed miRNA and mRNA expression profiles in human peripheral blood lymphocytes (PBLs) incubated in microgravity condition simulated by a...

  • HTML

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