Data Catalog

• Woman skeletal muscle transcriptome with bed rest and countermeasures.

  NASA Test —

  Microgravity has a dramatic impact on human physiology illustrated in particular with skeletal muscle impairment. A thorough understanding of the mechanisms leading to...

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• Bacillus subtilis spores PROTECT experiment Space-exposed and Mars-exposed vs. Earth-control

  NASA Test —

  Because of their ubiquity and resistance to spacecraft decontamination bacterial spores are considered likely potential forward contaminants on robotic missions to...

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• An environment with strong gravitational and magnetic field alterations synergizes to promote variations in Arabidopsis thaliana callus global transcriptional state

  NASA Test —

  Using diamagnetic levitation we have exposed A. thaliana in vitro callus cultures to five environments with different levels of effective gravity (from levitation i.e....

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• Proteomics and Transcriptomics analysis of Arabidopsis Seedlings in Microgravity

  NASA Test —

  On Earth plants are constantly exposed to a gravitational field of 1g. Gravity affects a plant in every step of its development. Germinating seedlings orient their...

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• Microgravity effect on C. elegans N2/VC (CERISE 8days)

  NASA Test —

  Microgravity effect on C. elegans gene expression was analysed by whole genome microarray. The worms were cultivated under microgravity for 8 days in the Japanese...

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• Genechip analysis of bone marrow osteoprogenitors exposed to microgravity

  NASA Test —

  In March 2006 murine Bone Marrow Stromal Cells (BMSC) were flown in the Soyuz 12S to the International Space Station to investigate the effects of microgravity on...

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• BRIC-23 GeneLab Process Verification Test: Staphylococcus aureus transcriptomic proteomic and metabolomic data

  NASA Test —

  Microbes interact with humans in complex ways and understanding how they respond to the spaceflight environment is important to the success of future manned...

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• Rodent Research-1 (RR1) NASA Validation Flight: Mouse adrenal gland transcriptomic proteomic and epigenomic data

  NASA Test —

  NASA s Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited...

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• Response of human lymphoblastoid cells to HZE (iron ions) or gamma-rays

  NASA Test —

  Transcriptional profiling of human lymphoblastoid TK6 cells comparing mock irradiated cells with cells exposed 24 hours previously to 1.67 Gy HZE (1 GeV/amu iron ions...

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• Multi-omic investigations of mouse liver subjected to simulated spaceflight freezing and storage protocols

  NASA Test —

  This study compares standard laboratory protocols for tissue freezing and storage with a simulation of the delayed processing of liver specimens and long-term storage...

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• Dynamic gene expression response to altered gravity in human T cells (parabolic flight)

  NASA Test —

  We investigated differentially regulated genes in human Jurkat T lymphocytic cells in 20s and 5min microgravity and in hypergravity and compared expression profiles to...

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• Identification of miRNAs involved in cell response to ionising radiation and modeled microgravity

  NASA Test —

  BACKGROUND: Ionizing radiation (IR) can be extremely harmful for human cells since an improper DNA-damage response (DDR) to IR can contribute to carcinogenesis...

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• Galactic cosmic radiation induces stable epigenome alterations relevant to human lung cancer

  NASA Test —

  Human deep space and planetary travel is limited by uncertainties regarding the health risks associated with exposure to galactic cosmic radiation (GCR) and in...

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• Microgravity effect on C. elegans N2/VC (CERISE 4 days)

  NASA Test —

  Microgravity effect on C. elegans gene expression was analysed by whole genome microarray. The worms were cultivated under microgravity for 4 days in the Japanese...

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• Response of the EPI-200 human 3-D skin model to high and low doses of protons

  NASA Test —

  Accumulating data suggest that the biological responses to high and low doses of radiation are qualitatively different necessitating the direct study of low dose...

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• Radiation responses in peripheral white blood cells of smokers and non-smokers

  NASA Test —

  Understanding the possible impact of potential confounding factors is necessary for any approach to radiation biodosimetry. Potential confounding factors have not been...

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• Human skin fibroblast mitochondrial depletion 0.5 Gy alpha-particle

  NASA Test —

  Mitochondrial DNA-depleted human skin fibroblasts (HSF rho0) with suppressed oxidative phosphorylation were characterized by significant changes in the expression of...

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• Response of human lymphoblastoid cells to activated medium

  NASA Test —

  Transcriptional profiling of human lymphoblastoid TK6 cells comparing mock irradiaed cells resuspended in fresh untreated RPMI 1640 medium with cells resuspended in...

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• Effects of a Closed Space Environment on Gene Expression in Hair Follicles of Astronauts in the International Space Station

  NASA Test —

  In recent times long-term stay has become a common occurrence in the International Space Station (ISS). However adaptation to the space environment can sometimes pose...

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• Effects of a Closed Space Environment on Gene Expression in Hair Follicles of Astronauts in the International Space Station

  NASA Test —

  In recent times long-term stay has become a common occurrence in the International Space Station (ISS). However adaptation to the space environment can sometimes pose...

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