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    • This is a Non-Federal dataset covered by different Terms of Use than Data.gov.

    Response of the EPI-200 human 3-D skin model to high and low doses of protons

    Metadata Updated: February 22, 2025

    Accumulating data suggest that the biological responses to high and low doses of radiation are qualitatively different necessitating the direct study of low dose responses. Most such studies have utilized 2-dimensional culture systems which may not fully represent responses in 3-dimensional tissues. To gain insight into low dose responses in tissue we have profiled global gene expression in EPI-200 a 3-dimensional tissue model from MatTek that imitates the structure and function of human epidermis at 4 16 and 24 hours after exposure to high (2.5 Gy) and low (0.1 Gy) doses of low LET protons. Untreated controls and samples exposed to 10 cGy or to 2.5 Gy were analyzed at three different times (4 16 or 24 hours after exposure). Three biological repeats were performed for each condition

    Access & Use Information

    Public: This dataset is intended for public access and use. Non-Federal: This dataset is covered by different Terms of Use than Data.gov. License: No license information was provided.

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    Dates

    Metadata Created Date February 22, 2025
    Metadata Updated Date February 22, 2025
    Data Update Frequency irregular

    Metadata Source

    Harvested from nasa test json

    Other Data Resources

    Additional Metadata

    Resource Type Dataset
    Metadata Created Date February 22, 2025
    Metadata Updated Date February 22, 2025
    Publisher National Aeronautics and Space Administration
    Maintainer
    Identifier nasa_genelab_GLDS-92_pr2n-gka9
    Data First Published 2018-06-26
    Data Last Modified 2025-02-19
    Category Earth Science
    Public Access Level public
    Data Update Frequency irregular
    Bureau Code 026:00
    Metadata Context https://project-open-data.cio.gov/v1.1/schema/catalog.jsonld
    Schema Version https://project-open-data.cio.gov/v1.1/schema
    Catalog Describedby https://project-open-data.cio.gov/v1.1/schema/catalog.json
    Harvest Object Id 196923ca-db28-41ea-9144-4b83d338611e
    Harvest Source Id a73e0c30-4684-40ef-908e-d22e9e9e5f86
    Harvest Source Title nasa test json
    Homepage URL https://data.nasa.gov/d/pr2n-gka9
    Program Code 026:005
    Source Datajson Identifier True
    Source Hash 0210160c60ce483b63a337f7dbb0d0e37d4ba25e5119170a244598cf59facf67
    Source Schema Version 1.1

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