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Identification of miRNAs involved in cell response to ionising radiation and modeled microgravity
NASA Test —
BACKGROUND: Ionizing radiation (IR) can be extremely harmful for human cells since an improper DNA-damage response (DDR) to IR can contribute to carcinogenesis... -
Response of the EPI-200 human 3-D skin model to high and low doses of protons
NASA Test —
Accumulating data suggest that the biological responses to high and low doses of radiation are qualitatively different necessitating the direct study of low dose... -
Mouse fecal microbiome after exposure to high LET radiation
NASA Test —
Space travel is associated with continuous low-dose-rate exposure to high Linear Energy Transfer (LET) radiation. Pathophysiological manifestations after low-dose... -
Action of microgravity on root development
NASA Test —
Arabidopsis were grown on horizontal or vertical clinostat for 4 8 or 12 days. Seedlings on horizontal clinostat were in simulated microgravity and seedlings on... -
Gene expression profiling in human fibroblast after low-LET irradiation
NASA Test —
Exposure to radiation provokes cellular responses controlled in part by gene expression networks. MicroRNAs (miRNAs) are small non-coding RNAs which mostly regulate... -
Identification of miRNAs involved in cell response to ionising radiation and modeled microgravity
NASA Test —
BACKGROUND: Ionizing radiation (IR) can be extremely harmful for human cells since an improper DNA-damage response (DDR) to IR can contribute to carcinogenesis... -
Response of the EPI-200 human 3-D skin model to high and low doses of protons
NASA Test —
Accumulating data suggest that the biological responses to high and low doses of radiation are qualitatively different necessitating the direct study of low dose... -
RNA-seq analysis of mycobacteria stress response to microgravity
NASA Test —
The aim of this work is to determine whether mycobacteria have enhanced virulence during space travel and what mechanisms they use to adapt to microgravity. M. marinum... -
Transient gene expression profile changes of confluent human fibroblast cells in spaceflight
NASA Test —
Microgravity or an altered gravity environment from the static 1g has been shown to influence global gene expression patterns and protein levels in cultured cells or... -
RAD51 Interconnects Between DNA Replication DNA Repair and Immunity
NASA Test —
RAD51 a multifunctional protein plays a central role in DNA replication and homologous recombination repair and is known to be involved in cancer development. We... -
Microgravity induces proteomics changes involved in endoplasmic reticulum stress and mitochondrial protection
NASA Test —
To reveal outcomes of microgravity on molecular processes within the cellular environment we have employed a mass-spectrometry based proteomics approach. Proteomics... -
MicroRNA expression of C. elegans in space environment
NASA Test —
Entire microRNA expression were analyzed using the Filgen Array miRNA Caenorhabditis elegans 232 probes (Filgen). In the microRNA expression analysis we compared the... -
MicroRNA expression of C. elegans in space environment
NASA Test —
Entire microRNA expression were analyzed using the Filgen Array miRNA Caenorhabditis elegans 232 probes (Filgen). In the microRNA expression analysis we compared the... -
Gene expression in human peripheral blood 48 hours after exposure to ionizing radiation
NASA Test —
Analysis of human peripheral blood 48 hours after irradiation ex vivo with graded doses of gamma rays. Results have been used in building and testing classifiers to... -
Gene expression in human peripheral blood 48 hours after exposure to ionizing radiation
NASA Test —
Analysis of human peripheral blood 48 hours after irradiation ex vivo with graded doses of gamma rays. Results have been used in building and testing classifiers to... -
Microgravity induces proteomics changes involved in endoplasmic reticulum stress and mitochondrial protection
NASA Test —
To reveal outcomes of microgravity on molecular processes within the cellular environment we have employed a mass-spectrometry based proteomics approach. Proteomics... -
Action of microgravity on root development
NASA Test —
Arabidopsis were grown on horizontal or vertical clinostat for 4 8 or 12 days. Seedlings on horizontal clinostat were in simulated microgravity and seedlings on...