Data Catalog

• Woman skeletal muscle transcriptome with bed rest and countermeasures.

  NASA Test —

  Microgravity has a dramatic impact on human physiology illustrated in particular with skeletal muscle impairment. A thorough understanding of the mechanisms leading to...

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• Bacillus subtilis spores PROTECT experiment Space-exposed and Mars-exposed vs. Earth-control

  NASA Test —

  Because of their ubiquity and resistance to spacecraft decontamination bacterial spores are considered likely potential forward contaminants on robotic missions to...

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• An environment with strong gravitational and magnetic field alterations synergizes to promote variations in Arabidopsis thaliana callus global transcriptional state

  NASA Test —

  Using diamagnetic levitation we have exposed A. thaliana in vitro callus cultures to five environments with different levels of effective gravity (from levitation i.e....

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• Microgravity effect on C. elegans N2/VC (CERISE 8days)

  NASA Test —

  Microgravity effect on C. elegans gene expression was analysed by whole genome microarray. The worms were cultivated under microgravity for 8 days in the Japanese...

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• Genechip analysis of bone marrow osteoprogenitors exposed to microgravity

  NASA Test —

  In March 2006 murine Bone Marrow Stromal Cells (BMSC) were flown in the Soyuz 12S to the International Space Station to investigate the effects of microgravity on...

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• Response of human lymphoblastoid cells to HZE (iron ions) or gamma-rays

  NASA Test —

  Transcriptional profiling of human lymphoblastoid TK6 cells comparing mock irradiated cells with cells exposed 24 hours previously to 1.67 Gy HZE (1 GeV/amu iron ions...

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• Radiation responses in peripheral white blood cells of smokers and non-smokers

  NASA Test —

  Understanding the possible impact of potential confounding factors is necessary for any approach to radiation biodosimetry. Potential confounding factors have not been...

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• Human skin fibroblast mitochondrial depletion 0.5 Gy alpha-particle

  NASA Test —

  Mitochondrial DNA-depleted human skin fibroblasts (HSF rho0) with suppressed oxidative phosphorylation were characterized by significant changes in the expression of...

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• Response of human lymphoblastoid cells to activated medium

  NASA Test —

  Transcriptional profiling of human lymphoblastoid TK6 cells comparing mock irradiaed cells resuspended in fresh untreated RPMI 1640 medium with cells resuspended in...

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• DNA copy number analysis from mice with radiation-induced acute myeloid leukemia

  NASA Test —

  Certain mouse strains such as CBA C3H and RFM have high incidence of radiation-induced acute myeloid leukemia (AML). The data in this series wer generated by using...

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• Root transcriptome remodeling of Arabidopsis in response to high levels of magnesium sulfate

  NASA Test —

  Martian regolith (unconsolidated surface material) is a potential medium for plant growth in bioregenerative life support systems during manned missions on Mars....

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• IMR90 radiation bystander time-course experiment 0.5Gy alpha particle

  NASA Test —

  The radiation bystander effect is an important component of the overall biological response of tissues and organisms to ionizing radiation. Little is known about the...

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• Microarray Profile of Gene Expression during Osteoclast Differentiation in Modeled Microgravity

  NASA Test —

  Microgravity leads to a 10-15% loss of bone mass in astronauts during space flight. Osteoclast is the multinucleated bone resorbing cell. In this study we used NASA...

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• Bystander response to 2.5 Gy of protons in a human 3-dimensional skin model in 16 h after exposure

  NASA Test —

  Bystander mechanisms that originate in the areas surrounding a tissue damage presumably play an important role participating in wound healing and tissue remodeling....

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• Comparison of gene expression profiles of normal human bronchial epithelial cells in 2D and 3D cultural conditions

  NASA Test —

  The experiment is part of a project to study DNA repair process after ionizing radiation in organotypic 3-dimentional human bronchial epithlial cell culture. Human...

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• Transcription profiling by array of the response of Arabidopsis cultivar Columbia etiolated seedlings and undifferentiated tissue culture cells to the spaceflight environment

  NASA Test —

  We address a key baseline question of whether gene expression changes are induced by the orbital environment and then we ask whether undifferentiated cells cells...

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• T Cell Activation in Microgravity Compared to 1g (Earth s) Gravity

  NASA Test —

  This study tested the hypothesis that transcription of immediate early genes is inhibited in T cells activated in microgravity (mg). Immunosuppression during...

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• Identifying radiation exposure biomarkers from mouse blood transcriptome

  NASA Test —

  Here we present a whole-genome survey of the murine transcriptomic response to physiologically-relevant radiation doses 2 and 8 Gy. There are 18 distinct biological...

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• Expression data from SPHINX (SPaceflight of Huvec: an INtegrated eXperiment)

  NASA Test —

  Changes in the physical environment modulate cell responses and may lead to the impairment or even failure of tissue function as a result of mechanotransduction...

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• MESSAGE 2 space experiment with Rhodospirillum rubrum S1H

  NASA Test —

  R. rubrum S1H inoculated on solid agar rich media was sent to the ISS in October 2003 (MESSAGE-part 2 experiment). After 10 days flight R. rubrum cultures returned...

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