Data Catalog

• Identification of miRNAs involved in cell response to ionising radiation and modeled microgravity

  NASA Test —

  BACKGROUND: Ionizing radiation (IR) can be extremely harmful for human cells since an improper DNA-damage response (DDR) to IR can contribute to carcinogenesis...

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• Comparative gene expression analysis in the Arabidopsis thaliana root apex using RNA-seq and microarray transcriptome profiles

  NASA Test —

  The root apex is an important section of the plant root involved in environmental sensing and cellular development. Analyzing the gene profile of root apex in diverse...

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• Rodent Research-1 (RR1) National Lab Validation Flight: Mouse liver transcriptomic proteomic and epigenomic data

  NASA Test —

  The Rodent Reasearch-1 National Lab (RR-1 CASIS) experiment was performed to study the effect of microgravity on muscle wasting. RNA DNA and protein were purified from...

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• Transcription profiling by array of the response of Arabidopsis cultivar Columbia etiolated seedlings and undifferentiated tissue culture cells to the spaceflight environment

  NASA Test —

  We address a key baseline question of whether gene expression changes are induced by the orbital environment and then we ask whether undifferentiated cells cells...

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• Response of the EPI-200 human 3-D skin model to high and low doses of protons

  NASA Test —

  Accumulating data suggest that the biological responses to high and low doses of radiation are qualitatively different necessitating the direct study of low dose...

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• Rodent Research-1 (RR1) NASA Validation Flight: Mouse liver transcriptomic proteomic and epigenomic data

  NASA Test —

  RR-1 is a validation flight to evaluate the hardware operational and science capabilities of the Rodent Research Project on the ISS. RNA DNA and protein were purified...

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• Genomic and Proteomic characterization of Aspergillus niger isolated from the International Space Station

  NASA Test —

  Genomic and proteomic characterization of the Aspergillus niger isolate JSC-093350089 collected from U.S. segment surfaces of the International Space Station (ISS) is...

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• Synergistic effects of microgravity and space radiation (Nimblegen)

  NASA Test —

  Space radiations and microgravity both could cause DNA damage in cells but the effects of microgravity on DNA damage response to space radiations are still...

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• Targeting myostatin/activin A protects against skeletal muscle and bone loss during spaceflight [plasma proteomics]

  NASA Test —

  Among the physiological consequences of extended spaceflight are loss of skeletal muscle and bone mass. One signaling pathway that plays an important role in...

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• T Cell Activation in Microgravity Compared to 1g (Earth s) Gravity

  NASA Test —

  This study tested the hypothesis that transcription of immediate early genes is inhibited in T cells activated in microgravity (mg). Immunosuppression during...

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• Global DNA methylation profiling of radiation-induced rat mammary carcinomas

  NASA Test —

  To investigate DNA methylation patterns in rat mammary carcinomas induced by ionizing radiation. DNA methylation patterns were analyzed in radiation-induced rat...

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• Spaceflight adaptation requires organ specific alterations in the proteomes of Arabidopsis

  NASA Test —

  Life in spaceflight demonstrates remarkable adaptive processes within the specialized environments of space vehicles which are subject to the myriad of attending and...

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• The influence of simulated microgravity on the proteome of Daphnia magna

  NASA Test —

  Background/Objectives: The waterflea Daphnia is an interesting candidate for bioregenerative life support systems (BLSS). These animals are particularly promising...

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• Rodent Research-1 (RR1) NASA Validation Flight: Mouse kidney transcriptomic proteomic and epigenomic data

  NASA Test —

  NASA s Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited...

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• Arg1 functions in the physiological adaptation of undifferentiated plant cells to spaceflight

  NASA Test —

  In this study transcriptome profiling was used to gain insight into the spaceflight adaptation role of Altered response to gravity-1 (Arg1) a gene known to affect...

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• Expression Data from International C.elegans Experiment 1st

  NASA Test —

  The effect of microgravity on gene expression in C.elegans was comprehensively analysed by DNA microarray. This is the first DNA microarray analysis for C.elegans...

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• Dissecting Low Atmospheric Pressure Stress: Transcriptome Responses to the Components of Hypobaria in Arabidopsis [Experiment 2]

  NASA Test —

  Controlled hypobaria presents biology with an environment that is never encountered in terrestrial ecology yet the apparent components of hypobaria are stresses...

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• Gamma radiation and HZE treatment of seedlings in Arabidopsis

  NASA Test —

  Plants exhibit a robust transcriptional response to gamma radiation which includes the induction of transcripts required for homologous recombination and the...

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• Synergistic effects of space radiation and microgravity (miRNA WT and dys-mutant)

  NASA Test —

  Space radiations and microgravity both could cause DNA damage in cells but the effects of microgravity on DNA damage response to space radiations are still...

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• Global gene expression analysis highlights microgravity sensitive key genes in longissimus dorsi and tongue of 30 days space-flown mice

  NASA Test —

  Microgravity as well as chronic muscle disuse are two causes of low back pain originated at least in part from paraspinal muscle deconditioning. At present no study...

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