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    • This is a Non-Federal dataset covered by different Terms of Use than Data.gov.

    Exposure of zebrafish larvae to 3g and 5g hyper gravity between 5-6 days post-fertilization.

    Metadata Updated: February 22, 2025

    The general objective of the study was to determine modulation of gene expression by environmental factors, with a special emphasis on bone formation. For this reason, the specific period of treatment was chosen between 5-6 days post-fertilization (dpf), when bone formation and calcification are taking place. Zebrafish larvae were placed at 5 dpf into a Large Diameter Centrifuge and brought to a gravitational force of 3g or 5g for 24 hours. We show that this treatment causes a clear increase of bone formation, as illustrated by cranial skeleton staining of the bone matrix by Alizarin Red, by morphometric analysis of the resulting images and by gene expression studies of selected genes. Thus, a whole genome micro-array experiment was conducted to identify genes that may be involved in the observed effect on bone formation.

    Access & Use Information

    Public: This dataset is intended for public access and use. Non-Federal: This dataset is covered by different Terms of Use than Data.gov. License: us-pd

    Downloads & Resources

    Dates

    Metadata Created Date February 22, 2025
    Metadata Updated Date February 22, 2025
    Data Update Frequency irregular

    Metadata Source

    Harvested from nasa test json

    Other Data Resources

    Additional Metadata

    Resource Type Dataset
    Metadata Created Date February 22, 2025
    Metadata Updated Date February 22, 2025
    Publisher National Aeronautics and Space Administration
    Maintainer
    Identifier nasa_genelab_GLDS-123_qr4c-tdt5
    Data First Published 2021-05-21
    Data Last Modified 2025-02-19
    Category Earth Science
    Public Access Level public
    Data Update Frequency irregular
    Bureau Code 026:00
    Metadata Context https://project-open-data.cio.gov/v1.1/schema/catalog.jsonld
    Schema Version https://project-open-data.cio.gov/v1.1/schema
    Catalog Describedby https://project-open-data.cio.gov/v1.1/schema/catalog.json
    Harvest Object Id 5292790c-3d0f-4362-b776-ccc58cee7cae
    Harvest Source Id a73e0c30-4684-40ef-908e-d22e9e9e5f86
    Harvest Source Title nasa test json
    Homepage URL https://data.nasa.gov/d/qr4c-tdt5
    License http://www.usa.gov/publicdomain/label/1.0/
    Program Code 026:005
    Source Datajson Identifier True
    Source Hash 1135f0f05b433ddd49fa987ce9e56d82cb22e1ccc583ab6e6a2002f08e48ef5d
    Source Schema Version 1.1

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